ABSTRACT
Pleuropulmonary Blastoma [PPB] is a very rare, highly aggressive and malignant tumor that originates from either the lungs or pleura. It occurs mainly in children aged less than five or six years. It has poor prognosis with three different subtypes: cystic [type I], combined cystic and solid [type II] and solid [type III]. PPB is treated with aggressive multimodal therapies including surgery and chemotherapy. We present a case of 3.5 years old boy with PPB type II successfully treated with complete surgical resection followed by neoadjuvant chemotherapy
Subject(s)
Humans , Male , Pulmonary Blastoma/surgery , Pulmonary Blastoma/drug therapy , Lung Neoplasms , ChildABSTRACT
Pulmonary blastoma is a rare malignancy with various histopathological appearances in children which present as an intra-thoracic mass. In this case report we present a 4-year-old boy with pleuro-pulmonary blastoma which was unrecognized for several weeks and was managed as pleural effusion and pneumonia. We decided to present this case because of the diagnostic difficulties and radiographic appearances
Subject(s)
Humans , Male , Diagnosis, Differential , Pulmonary Blastoma/pathology , Tomography, X-Ray Computed , Prognosis , Child , Lung Neoplasms , Pulmonary Blastoma/drug therapyABSTRACT
Se presentan 3 casos de tumores primitivos de origen pleuropulmonar:2 blastomas pleuropulmonares y un mesotelioma.Se obtuvieron inicialmente remisiones completas con quimioterapia convencional,cirugía y en uncaso se agregó radioterapia.Un paciente murió a los 14 meses y 2 están en progresión de enfermedad 12 y 14 meses después del diagnóstico.Terapia multimodal,cirugía,poliquimioterapia y radioterapia,juegan un rol importante en el tratamiento de estos tumores,sin embargo es insuficiente y no previenen la recurrencia local y/o metástasis.Se hace hincapié en el mal pronóstico de este tipo de tumores
Subject(s)
Humans , Child, Preschool , Mesothelioma/diagnosis , Mesothelioma/surgery , Pulmonary Blastoma/diagnosis , Pulmonary Blastoma/surgery , Mesothelioma/drug therapy , Mesothelioma/radiotherapy , Pulmonary Blastoma/drug therapy , Pulmonary Blastoma/radiotherapyABSTRACT
Se presenta el caso de un paciente de 18 anos de edad, de raza blanca y sexo masculino, con manifestaciones respiratorias de tos, expectoracion, dolor toracico y rayos X de torax con una masa del lobulo superior izquierdo. Despues de pleurotomia minima y biopsia se le diagnostico un blastoma pulmonar. Se le realizo neumectomia y posteriormente, se le administro poliquimioterapia